Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212937 | 0.77 | NPC1 (0.47) | ALDH1A1MAPTKMT2ASMN1; SMN2PTPN1 | |
| SCHEMBL7212927 | 0.75 | S1PR4 (0.38) | ALDH1A1MAPK1MAPTSMN1; SMN2POLB | |
| SCHEMBL28889636 | 0.70 | ALDH1A1 (0.52) | KCNN4ALDH1A1ALOX15MAPK1MAPT | |
| SCHEMBL25291817 | 0.69 | MAPT (0.52) | KCNN4ALDH1A1ALOX15MAPK1MAPT | |
| SCHEMBL112703 | 0.65 | MAPT (0.55) | KCNN4ALDH1A1ALOX15MAPK1MAPT | |
| SCHEMBL8849102 | 0.65 | ALDH1A1 (0.54) | KCNN4ALDH1A1ALOX15MAPK1MAPT | |
| SCHEMBL1014613 | 0.65 | ALDH1A1 (0.54) | KCNN4ALDH1A1ALOX15MAPK1MAPT | |
| SCHEMBL7208533 | 0.64 | CYP2C19 (0.39) | KCNN4MAPK1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8913938 | 0.63 | MAPK1 (0.50) | KCNN4ALDH1A1ALOX15MAPK1MAPT | |
| SCHEMBL28004816 | 0.63 | ALDH1A1 (0.52) | KCNN4ALDH1A1ALOX15MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |