Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642443 | 1.00 | THRA (0.73) | THRATHRB | |
| SCHEMBL4961521 | 0.94 | THRA (0.65) | THRATHRB | |
| SCHEMBL4965095 | 0.91 | THRA (0.72) | THRATHRB | |
| SCHEMBL7213674 | 0.91 | THRA (0.72) | THRATHRB | |
| SCHEMBL3866533 | 0.88 | THRA (0.79) | THRATHRB | |
| Axitirome SCHEMBL126256 | 0.85 | THRA (1.00) | THRATHRB | |
| Axitirome SCHEMBL29381397 | 0.85 | THRA (1.00) | THRATHRB | |
| SCHEMBL5394369 | 0.85 | THRB (0.74) | THRATHRB | |
| SCHEMBL4962611 | 0.83 | THRA (1.00) | THRATHRB | |
| SCHEMBL4966493 | 0.81 | THRA (0.83) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268404-A1 | MALONAMIC ACIDS AND DERIVATIVES THEREOF AS THYROID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072692-A1 | MALONAMIC ACIDS AND DERIVATIVES THEREOF AS THYROID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2001-10-04 | — | — | WO | disclosed |