SCHEMBL7213704

SCHEMBL7213704

C=CC=CC=CCc1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.38
IDO1 P14902 3/20 0.37
CNR2 P34972 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAOB P27338 1/20 0.33
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
ACHE P22303 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12544858 0.82 CNR2 (0.35) AGXTIDO1CNR2ALDH1A1TSHR
SCHEMBL13816709 0.80 CYP3A4 (0.38) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL7209313 0.79 ALDH1A1 (0.61) AGXTIDO1TAAR1ALDH1A1TP53
SCHEMBL11262502 0.79 MAOB (0.58) AGXTIDO1ALDH1A1TP53TSHR
SCHEMBL11400752 0.78 MAOB (0.52) AGXTIDO1CYP1A2CYP2A6TAAR1
SCHEMBL21969570 0.76 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL30753808 0.75 AGXT (0.40) AGXTIDO1CYP1A2CYP2A6TAAR1
SCHEMBL2300480 0.75 AGXT (0.40) AGXTIDO1CYP1A2CYP2A6TAAR1
SCHEMBL1455258 0.74 AGXT (0.43) AGXTIDO1CNR2CYP1A2CYP2A6
SCHEMBL10696598 0.74 IDO1 (0.42) AGXTIDO1CNR2CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339671-A2 1,7 AND 1,9-DIARYLPOLYMETHINE SALTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2003-09-03 EP disclosed
WO-2002046139-A2 1,7 AND 1,9-DIARYLPOLYMETHINE SALTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2002-06-13 WO disclosed