SCHEMBL7209313

SCHEMBL7209313

C=CC=CC=CCc1ccc(OC)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
ALOX15 P16050 2/20 0.61
TP53 P04637 1/20 0.61
CYP3A4 P08684 1/20 0.61
TSHR P16473 1/20 0.61
ALOX12 P18054 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
IDO1 P14902 5/20 0.44
AGXT P21549 2/20 0.44
LTA4H P09960 1/20 0.44
APLNR P35414 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
SLC6A4 P31645 1/20 0.38
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21969570 0.82 ALDH1A1 (0.39) ALDH1A1ALOX15TP53CYP3A4TSHR
SCHEMBL11437812 0.80 ALDH1A1 (0.68) ALDH1A1ALOX15TP53CYP3A4TSHR
SCHEMBL12335546 0.80 IDO1 (0.50) ALDH1A1IDO1AGXTTAAR1SIGMAR1
SCHEMBL7213704 0.79 AGXT (0.38) ALDH1A1ALOX15TP53CYP3A4TSHR
SCHEMBL28807469 0.78 ALDH1A1 (0.55) ALDH1A1ALOX15TP53CYP3A4TSHR
SCHEMBL6803104 0.77 ALDH1A1 (0.64) ALDH1A1ALOX15TP53CYP3A4TSHR
SCHEMBL11036979 0.77 ALDH1A1 (0.70) ALDH1A1ALOX15TP53CYP3A4TSHR
Estragole SCHEMBL57204 0.77 ALDH1A1 (1.00) ALDH1A1ALOX15TP53CYP3A4TSHR
Estragole SCHEMBL900647 0.77 ALDH1A1 (1.00) ALDH1A1ALOX15TP53CYP3A4TSHR
Estragole SCHEMBL28095175 0.77 ALDH1A1 (1.00) ALDH1A1ALOX15TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339671-A2 1,7 AND 1,9-DIARYLPOLYMETHINE SALTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2003-09-03 EP disclosed
WO-2002046139-A2 1,7 AND 1,9-DIARYLPOLYMETHINE SALTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2002-06-13 WO disclosed