Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718866 | 0.86 | HTR1A (0.75) | HTR1ASLC6A4HTR7KCNH2 | |
| SCHEMBL7466625 | 0.85 | HTR1A (0.73) | HTR1ASLC6A4HTR7KCNH2 | |
| SCHEMBL7082302 | 0.85 | HTR1A (0.70) | HTR1ASLC6A4HTR7 | |
| SCHEMBL7461356 | 0.84 | HTR1A (0.76) | HTR1ASLC6A4HTR7KCNH2 | |
| SCHEMBL7214578 | 0.82 | HTR1A (1.00) | HTR1ASLC6A4HTR7 | |
| SCHEMBL29534340 | 0.81 | HTR1A (0.62) | HTR1ASLC6A4HTR7 | |
| SCHEMBL28707500 | 0.81 | HTR1A (0.62) | HTR1ASLC6A4HTR7 | |
| SCHEMBL28715727 | 0.81 | HTR1A (0.62) | HTR1AHTR7 | |
| SCHEMBL29534971 | 0.81 | HTR1A (0.62) | HTR1AHTR7 | |
| SCHEMBL28715827 | 0.81 | HTR1A (0.61) | HTR1ASLC6A4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610712-B2 | Treating serotonin-related central nervous system disorders | WYETH | 2003-08-26 | — | — | US | claimed |
| WO-2002048105-A2 | ARYLOXY PIPERIDINYL DERIVATIVES FOR THE TREATMENT OF DEPRESSION | WYETH (US) | 2002-06-20 | — | — | WO | claimed |
| US-6610712-B2 | Treating serotonin-related central nervous system disorders | WYETH | 2003-08-26 | — | — | US | disclosed |
| US-20020091141-A1 | Aryloxy piperidinyl derivatives for the treatment of depression | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091141-A1 | Aryloxy piperidinyl derivatives for the treatment of depression | HTR2C, HTR1A, OPRD1 | HTR1A 2/4885SLC6A4 39/4885HTR7 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.