Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220101 | 0.84 | HPGD (0.46) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL7214349 | 0.82 | POLB (0.47) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7213607 | 0.82 | POLB (0.49) | CA1SMN1; SMN2ALOX15KDM4EALDH1A1 | |
| SCHEMBL15526785 | 0.80 | MAPT (0.57) | MAPTCA1CA2PLK1NPC1 | |
| SCHEMBL7219751 | 0.80 | HTT (0.54) | MAPTNPC1SMN1; SMN2KDM4EHTT | |
| SCHEMBL6418333 | 0.76 | MAPT (0.64) | MAPTCA1CA2PLK1NPC1 | |
| SCHEMBL8014083 | 0.75 | MAPT (0.62) | MAPTCA1CA2PLK1NPC1 | |
| SCHEMBL3286749 | 0.74 | CYP2B6 (0.48) | MAPTRAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL28456891 | 0.72 | MAPT (0.58) | MAPTCA1CA2PLK1NPC1 | |
| SCHEMBL11665996 | 0.72 | CA1 (0.61) | MAPTCA1CA2PLK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |