Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214349 | 0.86 | POLB (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7213607 | 0.86 | POLB (0.49) | HPGDALDH1A1HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL7213853 | 0.84 | MAPT (0.50) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8650991 | 0.78 | CTSL (0.36) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16375412 | 0.75 | ALDH1A1 (0.46) | HPGDALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL8173747 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GAAHDAC1HDAC6NPC1 | |
| SCHEMBL2264435 | 0.74 | ALDH1A1 (0.61) | HPGDALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL9855344 | 0.73 | HPGD (0.47) | HPGDALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL8862625 | 0.72 | ANO1 (0.42) | HPGDALDH1A1GAANPC1RAB9A | |
| SCHEMBL14609698 | 0.72 | ANO1 (0.42) | HPGDALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |