Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220101 | 0.86 | HPGD (0.46) | SMN1; SMN2LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL7214349 | 0.84 | POLB (0.47) | POLBSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL9602976 | 0.83 | KMT2A (0.45) | POLBLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL7213853 | 0.82 | MAPT (0.50) | CYP2C9SMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL4967949 | 0.80 | CTSL (0.59) | POLBCTSLCYP2C9SMN1; SMN2EPHX1 | |
| SCHEMBL24571837 | 0.78 | POLB (0.56) | POLBCYP2C9SMN1; SMN2EPHX1LMNA | |
| SCHEMBL13994623 | 0.78 | POLB (0.56) | POLBCYP2C9SMN1; SMN2EPHX1LMNA | |
| SCHEMBL7215966 | 0.77 | KMT2A (0.46) | POLBCTSLSMN1; SMN2CTSSCTSK | |
| SCHEMBL16376235 | 0.74 | POLB (0.53) | POLBCTSLCYP2C9SMN1; SMN2EPHX1 | |
| SCHEMBL1233442 | 0.73 | POLB (0.59) | POLBCYP2C9SMN1; SMN2EPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |