SCHEMBL7214068

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7369833	0.89	ROCK1 (0.46)	ROCK1ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL7219345	0.89	ALDH1A1 (0.40)	ROCK1ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL6436780	0.81	EGFR (0.44)	ROCK1ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL31595916	0.81	EGFR (0.44)	ROCK1ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL1204986	0.77	TRPA1 (0.61)	ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
	SCHEMBL1093339	0.76	TRPA1 (0.54)	ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
	SCHEMBL31595996	0.72	EGFR (0.44)	ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
	SCHEMBL6439627	0.72	EGFR (0.44)	ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
	SCHEMBL28187432	0.72	ROCK1 (0.46)	ROCK1ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL4385700	0.70	ROCK1 (0.45)	ROCK1CYP1A2CYP2C9CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.