Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672464 | 0.72 | HTR2A (0.60) | DRD2DRD1 | |
| SCHEMBL16938669 | 0.72 | HTR2A (0.60) | DRD2DRD1 | |
| SCHEMBL29383346 | 0.72 | HTR2A (0.60) | DRD2DRD1 | |
| SCHEMBL3670524 | 0.72 | HTR2A (0.60) | DRD2DRD1 | |
| Bromide SCHEMBL11010072 | 0.68 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4DRD2DRD1 | |
| SCHEMBL8506306 | 0.65 | DRD1 (0.42) | DRD2DRD1 | |
| SCHEMBL13004111 | 0.64 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4DRD2DRD1 | |
| SCHEMBL11272633 | 0.64 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3199731 | 0.64 | DRD2 (0.51) | SLC6A2SLC6A3SLC6A4DRD2DRD1 | |
| SCHEMBL11098069 | 0.63 | SLC6A2 (0.72) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645975-B1 | Reducing, deprotecting and optionally alkylating chemical intermediates to form 8,9-dihydroxy-2,3,7,11b-tetrahydro-1H-naphtho(1,2,3-de)isoquinoline, used as dopamine receptor agonists | PURDUE RESEARCH FOUNDATION | 2003-11-11 | — | — | US | disclosed |