SCHEMBL7214276

SCHEMBL7214276

[Li]c1c2ccccc2cc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
HSD17B10 Q99714 5/20 0.50
HIF1A Q16665 2/20 0.50
CYP1B1 Q16678 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
HTR2A P28223 1/20 0.48
CYP1A2 P05177 4/20 0.46
HPGD P15428 4/20 0.46
GLA P06280 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP2C19 P33261 1/20 0.46
CYP2A6 P11509 3/20 0.45
TSHR P16473 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
ACHE P22303 2/20 0.44
CYP3A4 P08684 1/20 0.44
ERBB2 P04626 1/20 0.44
FYN P06241 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139837 0.81 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL29658168 0.81 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL2139458 0.77 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL14878583 0.77 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL149754 0.75 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
Hydrochloric Acid SCHEMBL28826356 0.74 ALDH1A1 (0.48) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
Triphenylene SCHEMBL28075721 0.74 HPRT1 (0.59) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL28383579 0.73 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL4852007 0.73 HSD17B10 (0.60) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL5198472 0.72 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660408-B1 Having diarylamino substituted diaryl, triaryl or tetraaryl light emitting, electron transporting material; high performance and luminance NEC CORPORATION (JP) 2003-12-09 US disclosed
US-6582837-B1 Device having one or more organic thin layers including luminescent layer between anode and cathode, wherein at least one layer contains selected compound or compounds; exhibits higher-luminance luminescence than conventional device NEC CORPORATION (JP) 2003-06-24 US disclosed
EP-0365495-B1 9-Anthrylalkyl compounds, their preparation and their use EKA NOBEL AB (SE) 1994-03-16 EP disclosed
US-5128120-A Use of 9-anthrylalkyl compounds as derivatization reagents for separation and detection purposes EKA NOBEL AB (SE) 1992-07-07 US disclosed
US-5015755-A 9-anthrylalkyl compounds EKA NOBEL AB (SE) 1991-05-14 US disclosed
EP-0365495-A2 9-Anthrylalkyl compounds, their preparation and their use Eka Nobel Aktiebolag (SE) 1990-04-25 EP disclosed