SCHEMBL139837

SCHEMBL139837

[Li]c1cccc2c([Li])c3ccccc3cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.44
HSD17B10 Q99714 7/20 0.44
HIF1A Q16665 2/20 0.44
CYP1B1 Q16678 1/20 0.44
CYP1A2 P05177 7/20 0.36
HPGD P15428 5/20 0.36
TSHR P16473 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
TRPM4 Q8TD43 1/20 0.35
CYP2A6 P11509 4/20 0.35
TDP1 Q9NUW8 1/20 0.35
THRB P10828 1/20 0.34
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658168 1.00 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL11081181 0.81 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL7214276 0.81 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL31318311 0.79 ALDH1A1 (0.45) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL3082156 0.79 ALDH1A1 (0.45) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL238050 0.76 ALDH1A1 (0.53) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL29585978 0.76 ALDH1A1 (0.53) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
Methane SCHEMBL5212093 0.74 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL2139458 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL9017260 0.70 ALDH1A1 (0.34) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279527-B2 Method of converting anionic living end to protected free radical living end and applications thereof BRIDGESTONE CORPORATION (JP) 2007-10-09 US claimed
US-20060241265-A1 Method of converting anionic living end to protected free radical living end and applications thereof BRIDGESTONE CORPORATION (JP) 2006-10-26 US claimed
US-12515174-B2 Articles including an isoporous membrane disposed on a porous substrate and methods of making the same SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-06 US disclosed
US-12509556-B2 Functionalized hydrogenated interpolymer with non-hydrogenated segment BRIDGESTONE CORPORATION (JP) 2025-12-30 US disclosed
US-12410274-B2 Anionic dispersion polymerization process to make random copolymer rubber BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-20240309154-A1 GRAFTED EPDM POLYMERS AND RUBBER COMPOSITIONS EMPLOYING SAME BRIDGESTONE CORPORATION (JP) 2024-09-19 US disclosed
US-20240279401-A1 FUNCTIONALIZED HYDROGENATED INTERPOLYMER WITH NON-HYDROGENATED SEGMENT BRIDGESTONE CORPORATION (JP) 2024-08-22 US disclosed
US-20240158561-A1 ANIONIC DISPERSION POLYMERIZATION PROCESS TO MAKE RANDOM COPOLYMER RUBBER BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2024-05-16 US disclosed
US-11970581-B2 Functionalized hydrogenated interpolymer with non-hydrogenated segment BRIDGESTONE CORPORATION (JP) 2024-04-30 US disclosed
US-20240066473-A1 Articles Including an Isoporous Membrane Disposed on a Porous Substrate and Methods of Making the Same SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-02-29 US disclosed
US-20240034839-A1 FUNCTIONALIZED HYDROGENATED INTERPOLYMER WITH NON-HYDROGENATED SEGMENT BRIDGESTONE CORPORATION (JP) 2024-02-01 US disclosed
EP-0238784-A2 Process and system for preparing random copolymers having low vinyl contents THE FIRESTONE TIRE & RUBBER COMPANY (US) 1987-09-30 EP disclosed
US-4672097-A ANIONIC INITIATORS; SODIUM MAGNESIATE AND ORGANOLITHIUM COMPOUNDS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1987-06-09 US disclosed
EP-0215256-A1 Oligomeric oxolanyl alkanes as randomizers for copolymerization THE FIRESTONE TIRE & RUBBER COMPANY (US) 1987-03-25 EP disclosed
US-4647635-A Initiator systems for polymerization of 1,3-dienes or copolymers containing 1,3-dienes THE FIRESTONE TIRE & RUBBER COMPANY (US) 1987-03-03 US disclosed
EP-0096875-B1 LITHIUM ALKOXIDE DIAMINES AS MODIFIERS FOR POLYMERIZATION OF DIENES USING LITHIUM-BASED INITIATORS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1986-10-08 EP disclosed
US-4429091-A DYDROGENATED FURAN RESINS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-01-31 US disclosed
US-4429090-A CONJUGATED DIENES THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-01-31 US disclosed
EP-0096875-A1 Lithium alkoxide diamines as modifiers for polymerization of dienes using lithium-based initiators THE FIRESTONE TIRE & RUBBER COMPANY (US) 1983-12-28 EP disclosed
US-4401800-A Lithium alkoxide diamines as modifiers for polymerization of dienes using lithium-based initiators THE FIRESTONE TIRE & RUBBER COMPANY (US) 1983-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509556-B2 Functionalized hydrogenated interpolymer with non-hydrogenated segment VCL, ILK, RIF1 ALDH1A1 3138/4885HSD17B10 3584/4885HIF1A 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.