Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 4/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551942 | 0.86 | HSD17B3 (0.45) | HSD17B3HDAC1HDAC8HTR7PTGS2 | |
| SCHEMBL7220363 | 0.85 | HSD17B3 (0.49) | HSD17B3HTR7 | |
| SCHEMBL21551963 | 0.81 | HSD17B3 (0.42) | HSD17B3PTGS2STS | |
| SCHEMBL4198536 | 0.77 | HSD17B3 (0.70) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL18012808 | 0.77 | MAPT (0.38) | HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL23112845 | 0.77 | HSD17B3 (0.55) | HSD17B3HDAC1HDAC8THRASTS | |
| SCHEMBL1793318 | 0.76 | THRA (0.45) | HSD17B3HDAC1HDAC8THRATHRB | |
| SCHEMBL4293741 | 0.76 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL7907717 | 0.76 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL7788804 | 0.76 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559277-B2 | Soluble poly(bis-9,9'-fluorenes) comprise identical or different structural repeating units of the formula I, admixture with at least one additional fluorophore whose absorption band overlaps the emission band (fluorescent | VANTICO INC. | 2003-05-06 | — | — | US | disclosed |
| US-20020132911-A1 | Poly(9,9'-Spirobisfluorenes), their production and their use | VANTICO INC. AND VANTICO A&T U S INC. (NOW KNOWN AS HUNTSMAN ADVANCED MATERIALS AMERICAS INC.) | 2002-09-19 | — | — | US | disclosed |
| US-6380445-B1 | AROMATIC RESINS | VANTICO INC. | 2002-04-30 | — | — | US | disclosed |
| US-6132641-A | SOLVENT AND POLYMER OF POLY(BIS-9,9'-FLUORENE) AND FLUORESCENT DYE | VANTICO, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0863931-A2 | POLY(9,9'-SPIRO-BISFLUORENES), THE PRODUCTION AND USE OF SAME | Ciba SC Holding AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997020877-A2 | POLY(9,9'-SPIRO-BISFLUORENES), THE PRODUCTION AND USE OF SAME | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-06-12 | — | — | WO | disclosed |