Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 6/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631820 | 0.86 | UMPS (0.43) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL16631308 | 0.84 | UMPS (0.41) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL16631625 | 0.84 | UMPS (0.41) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL16631238 | 0.81 | UMPS (0.39) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL16631252 | 0.80 | UMPS (0.39) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL29771473 | 0.76 | PNP (0.55) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL16631268 | 0.75 | CDA (0.35) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL16631267 | 0.74 | CDA (0.34) | UMPSPNPHIF1AKDM4EGMNN | |
| SCHEMBL7209908 | 0.74 | UMPS (0.41) | UMPS | |
| SCHEMBL16631822 | 0.73 | OGA (0.35) | UMPSPNPLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617106-B1 | Methods for preparing oligonucleotides containing non-standard nucleotides | BENNER, STEVEN | 2003-09-09 | — | — | US | disclosed |
| US-6140496-A | Precursors for deoxyribonucleotides containing non-standard nucleosides | BENNER, STEVEN | 2000-10-31 | — | — | US | disclosed |