Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 3/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.36 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631308 | 1.00 | UMPS (0.41) | UMPSPYGLKDM4EGMNNLMNA | |
| SCHEMBL16631267 | 0.90 | CDA (0.34) | UMPSKDM4EGMNNLMNAMAPT | |
| SCHEMBL16631815 | 0.87 | OGA (0.34) | LMNATSHRPNPSLC5A2GSK3B | |
| SCHEMBL16631820 | 0.86 | UMPS (0.43) | UMPSPYGLKDM4EGMNNLMNA | |
| SCHEMBL7214397 | 0.84 | UMPS (0.44) | UMPSPYGLKDM4EGMNNLMNA | |
| SCHEMBL16631238 | 0.81 | UMPS (0.39) | UMPSPYGLKDM4EGMNNLMNA | |
| SCHEMBL16631252 | 0.80 | UMPS (0.39) | UMPSPYGLKDM4EGMNNLMNA | |
| SCHEMBL16631268 | 0.78 | CDA (0.35) | UMPSPYGLKDM4EGMNNLMNA | |
| SCHEMBL18079926 | 0.77 | P2RY2 (0.52) | — | |
| SCHEMBL16631306 | 0.75 | PYGL (0.44) | UMPSPYGLKDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |