SCHEMBL721442

SCHEMBL721442

O=C1NC2NC(=O)N(COC3CC4CCC3C4)C2N1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
ABL1 P00519 2/20 0.41
RIN1 Q13671 2/20 0.41
KDM4E B2RXH2 3/20 0.36
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.31
CYP19A1 P11511 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235529 0.75 CYP19A1 (0.35) CYP19A1
SCHEMBL723474 0.74 TDP1 (0.47) TDP1ABL1RIN1KDM4EKMT2A
SCHEMBL725248 0.73 TDP1 (0.46) TDP1ABL1RIN1KDM4EKMT2A
SCHEMBL723098 0.70 TDP1 (0.57) TDP1ABL1RIN1KDM4EKMT2A
SCHEMBL722579 0.69 TDP1 (0.43) TDP1ABL1RIN1KDM4EKMT2A
SCHEMBL2574552 0.69
SCHEMBL724731 0.68 CYP19A1 (0.35) KDM4EKMT2AMAPTCYP19A1
SCHEMBL725117 0.67 TDP1 (0.54) TDP1ABL1RIN1KDM4EKMT2A
SCHEMBL721824 0.67 TDP1 (0.60) TDP1ABL1RIN1KDM4EKMT2A
SCHEMBL11145933 0.67 TDP1 (0.72) TDP1ABL1RIN1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609468-A1 METHOD OF FORMING PATTERN AND DEVELOPER FOR USE IN THE METHOD FUJIFILM Corporation (JP) 2013-07-03 EP disclosed
WO-2013065878-A1 METHOD OF FORMING PATTERN AND COMPOSITION FOR CROSSLINKED LAYER FORMATION TO BE USED IN THE METHOD FUJIFILM CORPORATION (JP) 2013-05-10 WO disclosed
WO-2012026622-A1 METHOD OF FORMING PATTERN AND DEVELOPER FOR USE IN THE METHOD FUJIFILM CORPORATION (JP) 2012-03-01 WO disclosed