Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214727 | 0.76 | F2 (0.56) | F2PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL7214612 | 0.73 | TRPC5 (0.30) | — | |
| SCHEMBL7214003 | 0.71 | KDM4E (0.39) | KDM4EHPGD | |
| SCHEMBL23461191 | 0.60 | F2 (0.73) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7221015 | 0.59 | KDM4E (0.38) | KDM4EALDH1A1HPGD | |
| SCHEMBL7454648 | 0.58 | F2 (0.42) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7220252 | 0.57 | RAB9A (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL7213705 | 0.55 | NFATC1 (0.35) | ALDH1A1 | |
| SCHEMBL24479811 | 0.55 | KDM4E (0.60) | KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7216126 | 0.54 | NFATC1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1124822-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1124822-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |