Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216714 | 0.90 | SLC2A1 (0.51) | SLC2A1NQO1GSK3AGSK3BPAX8 | |
| SCHEMBL7214645 | 0.82 | SLC2A1 (0.61) | SLC2A1 | |
| Hydrochloric Acid SCHEMBL5919251 | 0.75 | SLC2A1 (0.37) | SLC2A1TERTHTR1B | |
| SCHEMBL7209590 | 0.73 | SLC2A1 (0.41) | SLC2A1TERTTSHRMEN1KMT2A | |
| SCHEMBL8216716 | 0.72 | SLC2A1 (0.73) | SLC2A1 | |
| SCHEMBL178861 | 0.69 | SLC2A1 (0.47) | SLC2A1 | |
| SCHEMBL5381846 | 0.67 | SLC2A1 (0.81) | SLC2A1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL8218149 | 0.66 | BCHE (0.47) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL178859 | 0.64 | MARS1 (0.51) | SLC2A1 | |
| Hydrochloric Acid SCHEMBL5388598 | 0.63 | SLC2A1 (0.63) | SLC2A1ALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003500397-A | — | — | 2003-01-07 | — | — | JP | claimed |
| WO-2000071524-A1 | 2-NH-PYRIDONES AND PYRIMIDONES AS MRS INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | claimed |
| WO-2000071524-A1 | 2-NH-PYRIDONES AND PYRIMIDONES AS MRS INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | disclosed |