Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878343 | 0.90 | HTR2C (0.37) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL290887 | 0.83 | HTR2A (0.39) | HTR2CSIGMAR1 | |
| SCHEMBL7214849 | 0.80 | HTR2A (0.40) | HTR2CSLC6A2SLC6A3 | |
| Acetonitrile SCHEMBL28222988 | 0.79 | CYP2D6 (0.31) | — | |
| SCHEMBL7817402 | 0.75 | HTR2C (0.43) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL10601800 | 0.74 | HTR2C (0.45) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL30790640 | 0.70 | HTR6 (0.33) | — | |
| SCHEMBL1598816 | 0.70 | HTR2C (0.39) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL17861414 | 0.70 | HTR2C (0.42) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| Phosphoric Acid SCHEMBL10597412 | 0.68 | CYP2D6 (0.38) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990006303-A1 | ARYLPIPERIDINE DERIVATIVES | PFIZER INC. (US) | 1990-06-14 | — | — | WO | disclosed |