Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 9/20 | 0.55 |
| ▸ | PDE4A | P27815 | 11/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353001 | 0.80 | KDM4E (0.66) | PDE4BPDE4APDE4DPDE4CRECQL | |
| SCHEMBL5610571 | 0.80 | RECQL (0.61) | PDE4BPDE4APDE4DPDE4CRECQL | |
| SCHEMBL27606600 | 0.79 | PDE4B (0.52) | PDE4BPDE4APDE4DPDE4CMAPK14 | |
| SCHEMBL6889304 | 0.79 | PDE4A (0.63) | PDE4BPDE4APDE4DPDE4C | |
| Nitrous Acid SCHEMBL7214855 | 0.79 | PDE4B (0.54) | PDE4BPDE4APDE4DPDE4CMAPK14 | |
| SCHEMBL7325038 | 0.79 | PDE4B (0.57) | PDE4BPDE4APDE4DPDE4CRECQL | |
| SCHEMBL7333965 | 0.79 | PDE4B (0.56) | PDE4BPDE4APDE4DPDE4CRECQL | |
| SCHEMBL8157358 | 0.78 | HDAC1 (0.56) | PDE4BPDE4APDE4DPDE4CMAPK14 | |
| Hydrochloric Acid SCHEMBL6887553 | 0.78 | PDE4A (0.62) | PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL7335293 | 0.78 | PDE4A (0.58) | PDE4BPDE4APDE4DPDE4CMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308440-A1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-07 | — | — | EP | disclosed |