Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.52 |
| ▸ | PDE4A | P27815 | 6/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976102 | 0.92 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4CRECQL | |
| SCHEMBL13111720 | 0.86 | RECQL (0.61) | PDE4BPDE4DPDE4APDE4CRECQL | |
| SCHEMBL2958828 | 0.81 | RECQL (0.60) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7361212 | 0.81 | RECQL (0.51) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7331685 | 0.81 | PDE4A (0.49) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7331695 | 0.81 | PDE4A (0.49) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7329994 | 0.80 | POLB (0.55) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL2371289 | 0.80 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL23717328 | 0.79 | RECQL (0.53) | PDE4BPDE4DPDE4APDE4CRECQL | |
| SCHEMBL7214858 | 0.79 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308440-A1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-07 | — | — | EP | disclosed |