Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20705133 | 0.90 | NR1H4 (0.36) | PDPK1POLBSSTR4SYKALDH1A1 | |
| SCHEMBL7219745 | 0.86 | NR1H4 (0.41) | F10POLBHDAC3HDAC1HDAC6 | |
| SCHEMBL7219743 | 0.86 | NR1H4 (0.41) | F10POLBHDAC3HDAC1HDAC6 | |
| SCHEMBL3743397 | 0.84 | PDPK1 (0.37) | PDPK1POLBHDAC3HDAC1HDAC6 | |
| SCHEMBL7220504 | 0.82 | PLG (0.43) | PDPK1HDAC3HDAC1HDAC6SSTR4 | |
| SCHEMBL3738636 | 0.80 | SSTR4 (0.37) | PDPK1HDAC3HDAC1HDAC6SSTR4 | |
| SCHEMBL3733168 | 0.80 | ROCK1 (0.38) | PDPK1HDAC3HDAC1HDAC6SSTR4 | |
| SCHEMBL20713655 | 0.79 | NR1H4 (0.35) | POLBSSTR4ALDH1A1 | |
| SCHEMBL13302732 | 0.77 | SYK (0.40) | PDPK1POLBSSTR4SYKALDH1A1 | |
| SCHEMBL18300427 | 0.76 | SYK (0.36) | PDPK1SSTR4SYKAAK1ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534535-B1 | Administering indole derivative as anticoagulant | MILLENNIUM PHARMACEUTICALS, INC. | 2003-03-18 | — | — | US | disclosed |
| WO-2001012600-A9 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC (US) | 2002-09-12 | — | — | WO | disclosed |
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1189879-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1159264-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2001012600-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000071512-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |