Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219743 | 1.00 | NR1H4 (0.41) | NR1H4F10KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7214930 | 0.86 | PDPK1 (0.35) | F10KDM4EALDH1A1HDAC3POLB | |
| SCHEMBL3743397 | 0.80 | PDPK1 (0.37) | KDM4EALDH1A1KMT2AHDAC3POLB | |
| SCHEMBL7220504 | 0.79 | PLG (0.43) | LMNAHDAC3MAPTBACE1HDAC1 | |
| SCHEMBL20705133 | 0.77 | NR1H4 (0.36) | NR1H4ALDH1A1POLB | |
| SCHEMBL3738636 | 0.76 | SSTR4 (0.37) | NR1H4HDAC3HDAC1HDAC6 | |
| SCHEMBL3733168 | 0.76 | ROCK1 (0.38) | NR1H4HDAC3HDAC1HDAC6 | |
| SCHEMBL20705108 | 0.75 | FBP1 (0.38) | NR1H4ALDH1A1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL22264109 | 0.75 | FBP1 (0.38) | NR1H4ALDH1A1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL476557 | 0.72 | P4HTM (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534535-B1 | Administering indole derivative as anticoagulant | MILLENNIUM PHARMACEUTICALS, INC. | 2003-03-18 | — | — | US | disclosed |
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |