Biphenyl

Biphenyl

SCHEMBL7214938

C1CCC(C2CCCCC2)CC1.CCCCCCCCOBO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.40
MEN1 O00255 1/20 0.37
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SIGMAR1 Q99720 2/20 0.36
CYP1A2 P05177 1/20 0.35
GBA1 P04062 2/20 0.35
CES2 O00748 1/20 0.35
EPHX1 P07099 5/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15092019 0.82
SCHEMBL21581256 0.82 THRB (0.44) NAAAMEN1THRBHTTKMT2A
SCHEMBL17937906 0.82 THRB (0.44) NAAAMEN1THRBHTTKMT2A
SCHEMBL21581268 0.82 THRB (0.44) NAAAMEN1THRBHTTKMT2A
SCHEMBL21581249 0.82 THRB (0.44) NAAAMEN1THRBHTTKMT2A
SCHEMBL1473434 0.82 THRB (0.44) NAAAMEN1THRBHTTKMT2A
SCHEMBL45784 0.80
Decane SCHEMBL11509639 0.76 ALDH1A1 (0.50) NAAATHRBALDH1A1SIGMAR1CYP1A2
Hexadecane SCHEMBL5581809 0.76 ALDH1A1 (0.50) NAAATHRBALDH1A1SIGMAR1CYP1A2
Decane SCHEMBL5581807 0.76 ALDH1A1 (0.50) NAAATHRBALDH1A1SIGMAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0974595-B1 PROCESS FOR PRODUCING BORON COMPOUNDS SHOWA DENKO KK (JP) 2003-10-01 EP disclosed
US-6140537-A REACTING AN ORGANIC OXYBORON COMPOUND WITH LITHIUM, MAGNESIUM, OR COMPOUND THEREOF; FORMING BORON ANION COMPOUND; ION EXCHANGING SHOWA DENKO K.K. (JP) 2000-10-31 US disclosed
EP-0974595-A1 PROCESS FOR PRODUCING BORON COMPOUNDS Showa Denko Kabushiki Kaisha (JP) 2000-01-26 EP disclosed