Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 6/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210045 | 0.93 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2HTR1A | |
| SCHEMBL1021477 | 0.85 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2HTR1A | |
| SCHEMBL1021480 | 0.85 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2HTR1A | |
| Trifluoroacetic Acid SCHEMBL8108321 | 0.84 | SLC6A4 (0.58) | SLC6A3SLC6A4SLC6A2HTR1A | |
| SCHEMBL7209977 | 0.75 | SLC6A2 (0.49) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5829872 | 0.75 | SLC6A2 (0.58) | SLC6A3SLC6A4SLC6A2HTR1A | |
| SCHEMBL5829493 | 0.74 | SLC6A4 (0.51) | SLC6A3SLC6A4SLC6A2HTR1A | |
| SCHEMBL5829491 | 0.74 | SLC6A4 (0.51) | SLC6A3SLC6A4SLC6A2HTR1A | |
| SCHEMBL7720436 | 0.74 | SLC6A2 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL13850008 | 0.73 | SLC6A2 (0.49) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984966-B1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH AS (DK) | 2003-01-29 | — | — | EP | disclosed |
| EP-0984966-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054182-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 1998-12-03 | — | — | WO | disclosed |