Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021477 | 0.88 | SLC6A3 (0.68) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL1021480 | 0.88 | SLC6A3 (0.68) | SLC6A4SLC6A3SLC6A2HTR1A | |
| Oxalic Acid SCHEMBL7214943 | 0.84 | SLC6A3 (0.54) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL7210045 | 0.81 | SLC6A3 (0.58) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL6553682 | 0.78 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL5830039 | 0.78 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL5829872 | 0.78 | SLC6A2 (0.58) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL6553255 | 0.77 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL5830141 | 0.77 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2HTR1A | |
| SCHEMBL5829491 | 0.77 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107307-A | PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0969005-A1 | Azabicyclic inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |