SCHEMBL7214946

SCHEMBL7214946

O=C(O)COCCNCO

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.39
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.33
CTH P32929 1/20 0.33
CBS P35520 1/20 0.33
THPO P40225 1/20 0.33
CYP1A2 P05177 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
THRB P10828 1/20 0.32
P2RY2 P41231 1/20 0.31
ALOX15 P16050 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7220626 0.86 EPHX2 (0.39) EPHX2CYP2C19TSHRCTHCBS
SCHEMBL7268276 0.84 SMN1; SMN2 (0.38) EPHX2CYP2C19TSHRCTHCBS
SCHEMBL27386798 0.84 SMN1; SMN2 (0.38) EPHX2CYP2C19TSHRCTHCBS
SCHEMBL29223001 0.83 EPHX2 (0.37) EPHX2CYP2C19TSHRCTHCBS
SCHEMBL19772732 0.80 EPHX2 (0.41) EPHX2CYP2C19TSHRCTHCBS
SCHEMBL25041340 0.78 SMN1; SMN2 (0.35) TSHRKDM4EALDH1A1
SCHEMBL26288350 0.77 SMN1; SMN2 (0.34) EPHX2CYP2C19TSHRCTHCBS
SCHEMBL17011631 0.76
SCHEMBL17833053 0.75 BLM (0.35) EPHX2CYP2C19KDM4EALDH1A1
SCHEMBL18251468 0.75 EPHX2 (0.42) EPHX2CYP2C19TSHRCYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6627772-B2 Preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine THE DOW CHEMICAL COMPANY 2003-09-30 US claimed
US-20020147360-A1 Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine ATHEY PHILLIP S (US) 2002-10-10 US claimed
US-20020010367-A1 Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine ATHEY PHILLIP S (US) 2002-01-24 US claimed
WO-2000076959-A2 INTERMEDIATES FOR THE PREPARATION OF (N)-[2-(CARBOXYMETHOXY) ETHYL]-(N)-(CARBOXYMETHYL) GLYCINE THE DOW CHEMICAL COMPANY (US) 2000-12-21 WO claimed
US-6627772-B2 Preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine THE DOW CHEMICAL COMPANY 2003-09-30 US disclosed
US-20020147360-A1 Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine ATHEY PHILLIP S (US) 2002-10-10 US disclosed
US-6392095-B2 HYDROLYSIS; HARD SURFACE CLEANING COMPOUNDS THE DOW CHEMICAL COMPANY 2002-05-21 US disclosed
US-20020010367-A1 Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine ATHEY PHILLIP S (US) 2002-01-24 US disclosed
US-6288263-B1 AMINO CARBOXY ETHERS AND SALTS THE DOW CHEMICAL COMPANY 2001-09-11 US disclosed
WO-2000076959-A2 INTERMEDIATES FOR THE PREPARATION OF (N)-[2-(CARBOXYMETHOXY) ETHYL]-(N)-(CARBOXYMETHYL) GLYCINE THE DOW CHEMICAL COMPANY (US) 2000-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010367-A1 Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine GNMT, GRM1, CPN1 EPHX2 602/4885CYP2C19 1947/4885TSHR 3882/4885
US-20020147360-A1 Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine GNMT, GRM1, CPN1 EPHX2 602/4885CYP2C19 1947/4885TSHR 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.