Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17229458 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL18882749 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL17089915 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL30433408 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL26689478 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL7720634 | 0.87 | LTA4H (0.36) | SMN1; SMN2CD274MEN1KMT2ABLM | |
| SCHEMBL7191311 | 0.87 | LMNA (0.38) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29004037 | 0.82 | LMNA (0.37) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL23748106 | 0.82 | MEN1 (0.37) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL21806634 | 0.82 | MEN1 (0.37) | SMN1; SMN2CD274KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016999-A2 | Compounds | Cargene Therapeutics Pte. Ltd. (SG) | 2023-02-16 | — | — | WO | disclosed |