SCHEMBL7215216

SCHEMBL7215216

CCCC1CCC(C2CCC(O)(c3ccccc3)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 12/20 0.47
OPRM1 P35372 11/20 0.47
OPRK1 P41145 11/20 0.47
OPRD1 P41143 8/20 0.42
CHRM4 P08173 2/20 0.38
POLB P06746 1/20 0.38
HSD11B1 P28845 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10910108 1.00 OPRL1 (0.47) OPRL1OPRM1OPRK1OPRD1CHRM4
SCHEMBL10910104 1.00 OPRL1 (0.47) OPRL1OPRM1OPRK1OPRD1CHRM4
SCHEMBL10893278 0.92 OPRL1 (0.44) OPRL1OPRM1OPRK1OPRD1
SCHEMBL11046287 0.92 OPRL1 (0.41) OPRL1OPRM1OPRK1OPRD1
SCHEMBL8452168 0.91 OPRL1 (0.49) OPRL1OPRM1OPRK1OPRD1CHRM4
SCHEMBL8452166 0.91 OPRL1 (0.49) OPRL1OPRM1OPRK1OPRD1CHRM4
SCHEMBL17072238 0.91 OPRL1 (0.48) OPRL1OPRM1OPRK1OPRD1CHRM4
SCHEMBL3480757 0.87 OPRM1 (0.41) OPRL1OPRM1OPRK1OPRD1
SCHEMBL11893261 0.85 OPRM1 (0.40) OPRL1OPRM1OPRK1OPRD1
SCHEMBL10606314 0.85 OPRM1 (0.43) OPRL1OPRM1OPRK1OPRD1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103725292-B Negative dielectric anisotropy liquid crystal compound and liquid crystal composition comprising same DAXIN MATERIALS CORP. (CN) 2016-01-20 CN disclosed
US-9133396-B2 Liquid crystal compound having negative dielectric anisotropy, and liquid crystal composition DAXIN MATERIALS CORP. (TW) 2015-09-15 US disclosed
US-9133396-B2 Liquid crystal compound having negative dielectric anisotropy, and liquid crystal composition DAXIN MATERIALS CORP. (TW) 2015-09-15 US disclosed
US-9133396-B2 Liquid crystal compound having negative dielectric anisotropy, and liquid crystal composition DAXIN MATERIALS CORP. (TW) 2015-09-15 US disclosed
CN-103725292-A Negative dielectric anisotropy liquid crystal compound and liquid crystal composition comprising same DAXIN MATERIALS CORP 2014-04-16 CN disclosed
US-6576303-B1 Negative and absolutely large Delta set- membership value CHISSO CORPORATION (JP) 2003-06-10 US disclosed
US-4620938-A Hydroterphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-04 US disclosed
US-4439340-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1984-03-27 US disclosed
EP-0094487-A1 Hydroterphenyls, their preparation and their use in dielectric liquid crystal material MERCK PATENT GmbH (DE) 1983-11-23 EP disclosed