Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893278 | 0.94 | OPRL1 (0.44) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL2892148 | 0.91 | OPRM1 (0.41) | OPRM1OPRL1OPRK1OPRD1CCR1 | |
| SCHEMBL11893261 | 0.87 | OPRM1 (0.40) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL10606317 | 0.87 | OPRM1 (0.43) | OPRM1OPRL1OPRK1OPRD1CCR1 | |
| SCHEMBL10606314 | 0.87 | OPRM1 (0.43) | OPRM1OPRL1OPRK1OPRD1CCR1 | |
| SCHEMBL7215216 | 0.87 | OPRL1 (0.47) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL10910104 | 0.87 | OPRL1 (0.47) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL10910108 | 0.87 | OPRL1 (0.47) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL11046287 | 0.85 | OPRL1 (0.41) | OPRM1OPRL1OPRK1OPRD1DRD2 | |
| SCHEMBL10804940 | 0.85 | OPRM1 (0.41) | OPRM1OPRL1OPRK1OPRD1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273264-B2 | Liquid-crystal compounds and LC media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8273264-B2 | Liquid-crystal compounds and LC media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8273264-B2 | Liquid-crystal compounds and LC media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-25 | — | — | US | disclosed |
| EP-2208775-B1 | Liquid crystalline compound and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2012-07-25 | — | — | EP | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2208775-A1 | Liquid crystal compounds and FK media | Merck Patent GmbH (DE) | 2010-07-21 | — | — | EP | disclosed |
| EP-2208775-A1 | Liquid crystal compounds and FK media | Merck Patent GmbH (DE) | 2010-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100181533-A1 | Liquid-crystal compounds and LC media | VCL, LCT, NEFM | OPRM1 1785/4885OPRL1 1786/4885OPRK1 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.