Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216358 | 0.93 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7211955 | 0.89 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7210640 | 0.86 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7215260 | 0.86 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL2466714 | 0.85 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7216225 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL7211992 | 0.82 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL7216255 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7216641 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8502462 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-0946507-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998025896-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-06-18 | — | — | WO | disclosed |