Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 14/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210640 | 0.93 | PTGS2 (0.64) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL5308967 | 0.89 | PTGS2 (0.65) | PTGS2PTGS1TUBB4ATUBBTUBA3C | |
| SCHEMBL7216358 | 0.86 | PTGS2 (0.62) | PTGS2PTGS1TUBB4ATUBBTUBA3C | |
| SCHEMBL7215325 | 0.86 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL7212043 | 0.85 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL7215303 | 0.82 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7215320 | 0.81 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL8504271 | 0.81 | PTGS2 (0.48) | PTGS2PTGS1ABCB11ALDH1A1TUBB4A | |
| SCHEMBL5314069 | 0.80 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL5311859 | 0.80 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |