Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359889 | 0.88 | PBRM1 (0.59) | PBRM1ALDH1A1KDM4ENPC1MITF | |
| SCHEMBL8071350 | 0.86 | KMT2A (0.50) | KDM4ENPC1LMNARAB9AMEN1 | |
| SCHEMBL1538494 | 0.83 | PBRM1 (0.58) | PBRM1ALDH1A1KDM4ENPC1MITF | |
| SCHEMBL633209 | 0.82 | PBRM1 (0.57) | PBRM1ALDH1A1KDM4ENPC1MITF | |
| SCHEMBL16871506 | 0.82 | ALDH1A1 (0.49) | PBRM1ALDH1A1KDM4ENPC1MITF | |
| SCHEMBL2208370 | 0.81 | PBRM1 (0.55) | PBRM1ALDH1A1KDM4ENPC1MITF | |
| 3-Aminobenzoic Acid SCHEMBL11499531 | 0.81 | PBRM1 (0.51) | PBRM1ALDH1A1KDM4ENPC1MITF | |
| SCHEMBL5562590 | 0.79 | HPGD (0.50) | KDM4EMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL3039881 | 0.79 | HDAC8 (0.56) | KDM4ENPC1LMNARAB9AMEN1 | |
| SCHEMBL25911130 | 0.79 | KDM4E (0.56) | ALDH1A1KDM4ENPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103788680-B | Preparation method of covering green-light benzimidazolone yellow HGRW for solvent treatment | LIANYUNGANG RIWA CHEMICAL CO LTD | 2015-07-22 | — | — | CN | claimed |
| CN-103788680-B | Preparation method of covering green-light benzimidazolone yellow HGRW for solvent treatment | LIANYUNGANG RIWA CHEMICAL CO LTD | 2015-07-22 | — | — | CN | disclosed |
| US-6509361-B1 | Inhibit the activity of p38 MAP kinase. Also contemplated by the invention are processes for the preparation of the contemplated compounds and for the use of a contemplated compound in treating a mammalian host having a p38 kinase or | PHARMACIA CORPORATION | 2003-01-21 | — | — | US | disclosed |