Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | PCNA | P12004 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 4/20 | 0.45 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188399 | 0.96 | FOLH1 (0.49) | SLC7A5PCNAFOLH1NAALAD2MME | |
| SCHEMBL188398 | 0.96 | FOLH1 (0.49) | SLC7A5PCNAFOLH1NAALAD2MME | |
| SCHEMBL28520123 | 0.94 | FOLH1 (0.48) | SLC7A5PCNAFOLH1NAALAD2MME | |
| Sulfuric Acid SCHEMBL8910597 | 0.90 | MEN1 (0.48) | SLC7A5PCNAFOLH1NAALAD2MME | |
| Sulfuric Acid SCHEMBL8910593 | 0.90 | MEN1 (0.48) | SLC7A5PCNAFOLH1NAALAD2MME | |
| SCHEMBL55972 | 0.87 | FOLH1 (0.56) | SLC7A5FOLH1NAALAD2MMEACE | |
| SCHEMBL3105902 | 0.87 | FOLH1 (0.56) | SLC7A5FOLH1NAALAD2MMEACE | |
| SCHEMBL55971 | 0.87 | FOLH1 (0.56) | SLC7A5FOLH1NAALAD2MMEACE | |
| SCHEMBL7215411 | 0.86 | MME (0.44) | SLC7A5MMEACECPA1ACE2 | |
| Methane SCHEMBL4610737 | 0.85 | FOLH1 (0.55) | SLC7A5FOLH1NAALAD2MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003072047-A2 | IDOTHYRONINE COMPOSITIONS | NEW RIVER PHARMACEUTICALS INC. (US) | 2003-09-04 | — | — | WO | disclosed |