Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL7215414 | 0.86 | SLC7A5 (0.46) | MMEACECPA1ACE2PPARG | |
| SCHEMBL188399 | 0.84 | FOLH1 (0.49) | MMEACECPA1ACE2PPARG | |
| SCHEMBL188398 | 0.84 | FOLH1 (0.49) | MMEACECPA1ACE2PPARG | |
| SCHEMBL28520123 | 0.83 | FOLH1 (0.48) | MMEACECPA1ACE2PPARG | |
| SCHEMBL4279536 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BPPARGPPARALDHA | |
| Sulfuric Acid SCHEMBL8910597 | 0.80 | MEN1 (0.48) | MMEACECPA1ACE2CA2 | |
| SCHEMBL8910599 | 0.80 | KDM4E (0.46) | MMEACECPA1ACE2ITGB3 | |
| Sulfuric Acid SCHEMBL8910593 | 0.80 | MEN1 (0.48) | MMEACECPA1ACE2CA2 | |
| SCHEMBL28038313 | 0.76 | CA2 (0.52) | MMEACECPA1ACE2CA2 | |
| SCHEMBL28038310 | 0.76 | CA2 (0.52) | MMEACECPA1ACE2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003072047-A2 | IDOTHYRONINE COMPOSITIONS | NEW RIVER PHARMACEUTICALS INC. (US) | 2003-09-04 | — | — | WO | disclosed |