Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.42 |
| ▸ | PCNA | P12004 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8910593 | 1.00 | MEN1 (0.48) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL188398 | 0.94 | FOLH1 (0.49) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL188399 | 0.94 | FOLH1 (0.49) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL28520123 | 0.93 | FOLH1 (0.48) | MEN1KMT2AL3MBTL1CA1CA2 | |
| Carbamic Acid SCHEMBL7215414 | 0.90 | SLC7A5 (0.46) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL8910599 | 0.86 | KDM4E (0.46) | CA2MMEACECPA1ACE2 | |
| SCHEMBL55972 | 0.85 | FOLH1 (0.56) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL55971 | 0.85 | FOLH1 (0.56) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL3105902 | 0.85 | FOLH1 (0.56) | MEN1KMT2AL3MBTL1CA1CA2 | |
| Methane SCHEMBL4610737 | 0.84 | FOLH1 (0.55) | MEN1KMT2AL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670380-A | QUANTITATIVE ANALYSIS OF PREGNANT WOMEN | VETERANS AFFAIRS, DEPARTMENT OF | 1997-09-23 | — | — | US | disclosed |