Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532215 | 0.83 | PGR (0.40) | PGRNR3C1LMNACYP3A4ABCB11 | |
| SCHEMBL5498124 | 0.82 | PGR (0.49) | PGRNR3C1LMNACYP3A4ABCB11 | |
| SCHEMBL8542951 | 0.82 | PGR (0.41) | PGRCYP17A1CYP21A2CYP19A1 | |
| SCHEMBL8538436 | 0.73 | CYP19A1 (0.35) | PGRHIF1AALDH1A1SHBGCYP17A1 | |
| SCHEMBL5700112 | 0.72 | CYP3A4 (0.65) | PGRNR3C1LMNACYP3A4ABCB11 | |
| SCHEMBL5495772 | 0.71 | AR (0.72) | PGRNR3C1AR | |
| SCHEMBL5499361 | 0.70 | NR3C1 (0.41) | PGRNR3C1LMNACYP3A4CYP17A1 | |
| SCHEMBL5496193 | 0.69 | PGR (0.54) | PGRNR3C1LMNACYP3A4ABCB11 | |
| SCHEMBL9019827 | 0.68 | NR3C1 (0.59) | PGRNR3C1LMNACYP3A4ABCB11 | |
| SCHEMBL8541047 | 0.68 | PGR (0.48) | PGRNR3C1LMNACYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1365765-A2 | THE USE OF ANTIGESTAGENS FOR INHIBITING ACCELERATED ENDOMETRIAL MATURATION DURING INFERTILITY TREATMENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002067910-A2 | THE USE OF ANTIGESTAGENS FOR INHIBITING ACCELERATED ENDOMETRIAL MATURATION DURING INFERTILITY TREATMENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-09-06 | — | — | WO | disclosed |