Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.67 |
| ▸ | TNF | P01375 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22345608 | 0.89 | CYP11B1 (0.61) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| SCHEMBL4142913 | 0.88 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| SCHEMBL30826274 | 0.88 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| Bromide SCHEMBL31253900 | 0.86 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31253891 | 0.86 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| SCHEMBL16756287 | 0.84 | CYP11B1 (0.66) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| SCHEMBL20715687 | 0.84 | CYP11B1 (0.66) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| SCHEMBL7436465 | 0.82 | CYP11B1 (0.55) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| SCHEMBL20550865 | 0.81 | CYP11B1 (0.69) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 | |
| SCHEMBL13907295 | 0.80 | CYP11B1 (0.89) | CYP11B1CYP11B2TNFHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097618-B1 | POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS | FRYS METALS INC DBA ALPHA METALS INC (US) | 2003-03-26 | — | — | EP | claimed |
| US-10479790-B2 | COMT inhibiting methods and compositions | LIEBER INSTITUTE FOR BRAIN DEVELOPMENT (US) | 2019-11-19 | — | — | US | disclosed |
| US-10035799-B2 | COMT inhibiting methods and compositions | LIEBER INSTITUTE FOR BRAIN DEVELOPMENT (US) | 2018-07-31 | — | — | US | disclosed |
| US-9865952-B2 | Plug contact with organic coating and printed circuit board arrangement | CONTINENTAL AUTOMOTIVE GMBH (DE) | 2018-01-09 | — | — | US | disclosed |
| US-20170179628-A1 | PLUG CONTACT WITH ORGANIC COATING AND PRINTED CIRCUIT BOARD ARRANGEMENT | CONTINENTAL AUTOMOTIVE GMBH (DE) | 2017-06-22 | — | — | US | disclosed |
| CN-101489553-A | Combinations of monoamine reuptake inhibitors and potassium channel activators | NEUROSEARCH AS (DK) | 2009-07-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035799-B2 | COMT inhibiting methods and compositions | COMT, SLC6A3, MAOA | CYP11B1 35/4885CYP11B2 65/4885TNF 4521/4885 |
| US-10479790-B2 | COMT inhibiting methods and compositions | COMT, SLC6A3, MAOA | CYP11B1 35/4885CYP11B2 65/4885TNF 4521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.