SCHEMBL7215809

SCHEMBL7215809

CC(C)OB(OCc1ccccc1)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
IDO1 P14902 1/20 0.38
HTT P42858 2/20 0.36
AGXT P21549 1/20 0.36
ALDH1A1 P00352 3/20 0.36
TRPA1 O75762 1/20 0.36
LIPE Q05469 1/20 0.36
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC6A2 P23975 2/20 0.35
TAAR1 Q96RJ0 2/20 0.35
MAOA P21397 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CYP2A6 P11509 1/20 0.35
ADORA2A P29274 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180519 0.71 TSHR (0.44) TSHRIDO1HTTAGXTALDH1A1
SCHEMBL7209991 0.71 CA4 (0.36) TSHRALDH1A1LMNAMEN1KMT2A
SCHEMBL7172642 0.69 LIPE (0.46) TSHRIDO1HTTAGXTALDH1A1
SCHEMBL15003 0.69 TSHR (0.52) TSHRIDO1HTTAGXTALDH1A1
SCHEMBL5952618 0.68 TSHR (0.41) TSHRHTTTRPA1MEN1KMT2A
SCHEMBL51017 0.68 TSHR (0.57) TSHRIDO1AGXTALDH1A1LIPE
SCHEMBL9504704 0.67 TSHR (0.50) TSHRIDO1HTTAGXTALDH1A1
Lithium SCHEMBL9504699 0.67 TSHR (0.50) TSHRIDO1HTTAGXTALDH1A1
Ammonia Solution, Strong SCHEMBL21518155 0.67 TSHR (0.50) TSHRIDO1HTTAGXTALDH1A1
SCHEMBL9557568 0.67 TSHR (0.44) TSHRIDO1AGXTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0974595-B1 PROCESS FOR PRODUCING BORON COMPOUNDS SHOWA DENKO KK (JP) 2003-10-01 EP disclosed
US-6140537-A REACTING AN ORGANIC OXYBORON COMPOUND WITH LITHIUM, MAGNESIUM, OR COMPOUND THEREOF; FORMING BORON ANION COMPOUND; ION EXCHANGING SHOWA DENKO K.K. (JP) 2000-10-31 US disclosed
EP-0974595-A1 PROCESS FOR PRODUCING BORON COMPOUNDS Showa Denko Kabushiki Kaisha (JP) 2000-01-26 EP disclosed