Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | GLA | P06280 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | IKBKB | O14920 | 1/20 | 0.59 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026879 | 1.00 | KDM4E (0.70) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL9025206 | 0.84 | ALDH1A1 (0.64) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL29513035 | 0.84 | ALDH1A1 (0.64) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL9495721 | 0.83 | LMNA (0.65) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4633547 | 0.83 | ALDH1A1 (0.63) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL1101766 | 0.83 | KDM4E (1.00) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL30173777 | 0.83 | KDM4E (1.00) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL19478160 | 0.81 | KDM4E (0.52) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL9495716 | 0.81 | ALDH1A1 (0.64) | KDM4EMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL4723975 | 0.80 | KDM4E (0.73) | KDM4EMAPTALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307513-A | 3-Aminobenzo [ b ] thiophene compound and preparation method and application thereof | 河南工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118307513-A | 3-Aminobenzo [ b ] thiophene compound and preparation method and application thereof | 河南工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-111440216-B | Synthesis method of iridium-containing complex | 北京夏禾科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-111440216-A | Synthesis method of iridium-containing complex | 北京夏禾科技有限公司 | 2020-07-24 | — | — | CN | disclosed |
| EP-2910555-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORP (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-2910555-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORP (US) | 2019-03-27 | — | — | EP | disclosed |
| US-9553274-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| US-9553274-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| US-9553274-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| US-9502656-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-11-22 | — | — | US | disclosed |
| WO-2012131297-A1 | PYRIDO [3',2' :4,5] THIENO [3, 2-D] PYRIMIDIN- 4 - YLAMINE DERIVATIVES AND THEIR THERAPEUTICAL USE | BAELL JONATHAN BAYLDON (AU) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012131297-A1 | PYRIDO [3',2' :4,5] THIENO [3, 2-D] PYRIMIDIN- 4 - YLAMINE DERIVATIVES AND THEIR THERAPEUTICAL USE | BAELL JONATHAN BAYLDON (AU) | 2012-10-04 | — | — | WO | disclosed |
| US-7176320-B2 | Benzimidazole derivative | TEIJIN LIMITED (JP) | 2007-02-13 | — | — | US | disclosed |
| US-6596726-B1 | Method of inhibiting epidermal growth factor by treating, with an effective inhibiting amount, a mammal, in need thereof inhibit the epidermal growth factor receptor and related receptors and, in particular, their tyrosine kinase enzyme | WARNER LAMBERT COMPANY | 2003-07-22 | — | — | US | disclosed |
| US-6133275-A | ALPHA 1 ADRENORECEPTOR ANTAGONISTS; TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER UROLOGICAL DISEASES E.G., BLADDER OUTLET OBSTRUCTION), NEUROGENIC BLADDER AND GYNECOLOGICAL SYNDROMES, E.G., DYSMENORRHEA; UTERINE MUSCLE RELAXANTS | ABBOTT LABORATORIES (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0808318-B1 | TRICYCLIC SUBSTITUTED HEXAHYDROBENZ[E]ISOINDOLE ALPHA-1 ADRENERGIC ANTAGONISTS | ABBOTT LAB (US) | 2000-06-28 | — | — | EP | disclosed |
| US-5679683-A | USEFUL FOR TREATING CANCER, ARTHRITIS, PSORIASIS, VASCULAR RESTENOSIS AND ANGIOGENESIS | WARNER-LAMBERT COMPANY (US) | 1997-10-21 | — | — | US | disclosed |
| US-5597823-A | TREATING BENIGN PROSTATIC HYPERPLASIA | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0741711-A1 | TRICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995019970-A1 | TRICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1995-07-27 | — | — | WO | disclosed |