Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL28389555 | 0.98 | NPC1 (0.44) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Biphenyl SCHEMBL28542072 | 0.92 | GAA (0.40) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Benzotriazole SCHEMBL18631930 | 0.91 | ALDH1A1 (0.39) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL20445532 | 0.91 | ALDH1A1 (0.39) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Benzotriazole SCHEMBL1019155 | 0.91 | ALDH1A1 (0.39) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Benzotriazole SCHEMBL10864546 | 0.89 | ALDH1A1 (0.38) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Benzotriazole SCHEMBL28664376 | 0.89 | MAPT (0.39) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Benzotriazole SCHEMBL28091111 | 0.89 | ALDH1A1 (0.38) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Benzotriazole SCHEMBL28212495 | 0.89 | NPC1 (0.38) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| Benzotriazole SCHEMBL6088869 | 0.89 | ALDH1A1 (0.41) | NPC1RAB9AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003500520-A | — | — | 2003-01-07 | — | — | JP | claimed |
| EP-1187894-A1 | HIGH STRESS ELECTRICAL OIL | ExxonMobil Research and Engineering Company (US) | 2002-03-20 | — | — | EP | claimed |
| US-6214776-B1 | SPECIALTY OILS WITH PHENOLIC ANTIOXIDANT ANS BENZOTRIAZOLE DIPHENYLAMINE METAL DEACTIVATOR | EXXON RESEARCH AND ENGINEERING COMPANY | 2001-04-10 | — | — | US | claimed |
| WO-2000071648-A1 | HIGH STRESS ELECTRICAL OIL | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2000-11-30 | — | — | WO | claimed |
| EP-1187894-A1 | HIGH STRESS ELECTRICAL OIL | ExxonMobil Research and Engineering Company (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6214776-B1 | SPECIALTY OILS WITH PHENOLIC ANTIOXIDANT ANS BENZOTRIAZOLE DIPHENYLAMINE METAL DEACTIVATOR | EXXON RESEARCH AND ENGINEERING COMPANY | 2001-04-10 | — | — | US | disclosed |
| WO-2000071648-A1 | HIGH STRESS ELECTRICAL OIL | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2000-11-30 | — | — | WO | disclosed |