Benzotriazole

Benzotriazole

SCHEMBL6088869

c1ccc2[nH]nnc2c1.c1ccc2[nH]nnc2c1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ABCB11 O95342 1/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MASP2 O00187 1/20 0.38
MEN1 O00255 1/20 0.38
NUDT1 P36639 1/20 0.38
KMT2A Q03164 1/20 0.38
AOC3 Q16853 1/20 0.38
TSHR P16473 1/20 0.38
GPR3 P46089 1/20 0.38
MAPT P10636 1/20 0.36
IDO1 P14902 2/20 0.36
CDK2 P24941 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzotriazole SCHEMBL8956 1.00
Benzotriazole SCHEMBL29381270 1.00
Benzotriazole SCHEMBL3018142 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1
Benzotriazole SCHEMBL343607 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1
Benzotriazole SCHEMBL416513 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1
Benzotriazole SCHEMBL1151651 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1
Benzotriazole SCHEMBL9359282 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1
Benzotriazole SCHEMBL4459859 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1
Benzotriazole SCHEMBL9979189 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1
Benzotriazole SCHEMBL9059391 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104804505-A Enhanced coating or layer GM GLOBAL TECH OPERATIONS INC 2015-07-29 CN claimed
US-20060235222-A1 Indole-derivative modulators of steroid hormone nuclear receptors ELI LILLY AND COMPANY (US) 2006-10-19 US claimed
EP-1597254-A1 INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS Eli Lilly and Company (US) 2005-11-23 EP claimed
WO-2004067529-A1 INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS ELI LILLY AND COMPANY (US) 2004-08-12 WO claimed
EP-0877783-B1 METHOD FOR SOLUBILIZING A BENZOTRIAZOLE WITH A THIADIAZOLE INFINEUM USA LP (US) 1999-07-28 EP claimed
CN-1024352-C Weather-resistant polyacetal resin composition POLYPLASTICS CO (JP) 1994-04-27 CN claimed
JP-57023071-A None JP disclosed
US-10133414-B2 Layered body for touch panel, and touch panel FUJIFILM CORPORATION (JP) 2018-11-20 US disclosed
CN-103339191-B Water absorbency resin composition and the laminated body employing this water absorbency resin composition 大赛璐-湛新株式会社 2016-08-10 CN disclosed
US-20160132183-A1 LAYERED BODY FOR TOUCH PANEL, AND TOUCH PANEL FUJIFILM CORPORATION (JP) 2016-05-12 US disclosed
US-20160104680-A1 METHOD OF FORMING METAL INTERCONNECTIONS OF SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2016-04-14 US disclosed
CN-103429600-B Novel cpd, near infrared ray absorption and the compound resin composition containing it ADEKA CORP. (JP) 2015-11-25 CN disclosed
CN-103554650-B Transparentizing agent composition containing sorbitol compounds and the manufacture method of polypropylene-based resin composition ASAHI DENKA CO., LTD. (JP) 2015-11-18 CN disclosed
WO-2004067529-A1 INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS ELI LILLY AND COMPANY (US) 2004-08-12 WO disclosed
CN-1394223-A Granular composite additive for polyolefin, process for producing the same, and polyolefin composition containing the same ASAHI DENKA KOGYO KK (JP) 2003-01-29 CN disclosed
US-5879438-A CONTAINING SPECIFIC ELECTRON ACCEPTING LIGHTFASTNESS PROVIDING AGENT THE PILOT INK CO., LTD. (JP) 1999-03-09 US disclosed
CN-1066675-A The low-sulfur diesel fuels that contains organometallic complex LUBRIZOL CORP (US) 1992-12-02 CN disclosed
CN-1019124-B WEATHER-RESISTANT POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 1992-11-18 CN disclosed
CN-1040806-A WEATHER-RESISTANT POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 1990-03-28 CN disclosed
JP-S5723071-A ANTICORROSIVE FOR METAL CHIYODA KAGAKU KENKYUSHO:KK 1982-02-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235222-A1 Indole-derivative modulators of steroid hormone nuclear receptors NR3C2, NR5A1, MC2R ALDH1A1 1544/4885KDM4E 3154/4885NPC1 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.