Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.51 |
| ▸ | TUBB | P07437 | 4/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222428 | 0.90 | GAA (0.55) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL7221208 | 0.87 | PTGS2 (0.59) | GAAKDM4ELMNAPTGS2PTGS1 | |
| SCHEMBL7218478 | 0.86 | PTGS2 (0.60) | GAAALDH1A1KDM4EPTGS2TUBB4A | |
| SCHEMBL7221860 | 0.84 | PTGS2 (0.71) | ALDH1A1KDM4EPTGS2TUBB4ATUBB | |
| SCHEMBL7215562 | 0.83 | PTGS2 (0.50) | GAAMAPTPTGS2TUBB4ATUBB | |
| SCHEMBL7217007 | 0.83 | PTGS2 (0.52) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL7221708 | 0.82 | PTGS2 (0.52) | GAAMAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL7215555 | 0.77 | KDM4E (0.60) | GAAALDH1A1KDM4EPTGS2TUBB4A | |
| SCHEMBL7221568 | 0.75 | GRIA1 (0.53) | GAAKDM4ELMNAPTGS2PTGS1 | |
| SCHEMBL7221055 | 0.74 | GRIA1 (0.54) | GAAALDH1A1KDM4EPTGS2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670365-B1 | Treatment of inflamation and/or cyclooxygenase-mediated diseases, reduced ulcerogenic effects; 2-phenyl-3-(4-methylsulfonylphenyl)imidazo(1,2-a)pyrimidine | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2003-12-30 | — | — | US | disclosed |