Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4438089 | 1.00 | GAA (0.53) | GAAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL10569475 | 0.88 | MAPT (0.45) | ALDH1A1KMT2AHTR2AHTTMAPT | |
| SCHEMBL3861174 | 0.86 | IDO1 (0.43) | ALDH1A1KMT2AHTR2AHTTMAPT | |
| SCHEMBL7294874 | 0.86 | IDO1 (0.43) | ALDH1A1KMT2AHTR2AHTTMAPT | |
| SCHEMBL8716890 | 0.86 | RAB9A (0.47) | ALDH1A1HTTMAPTRAB9AATM | |
| SCHEMBL5481199 | 0.86 | RAB9A (0.49) | KMT2AHTR2AHTTMAPTRAB9A | |
| SCHEMBL6285272 | 0.83 | CNR2 (0.50) | ALDH1A1KMT2AMEN1ATM | |
| SCHEMBL5484162 | 0.83 | ALDH1A1 (0.49) | GAAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7216770 | 0.83 | FFAR1 (0.53) | GAAALDH1A1MAPK1KMT2AHTT | |
| SCHEMBL5183992 | 0.83 | ATM (0.55) | GAAALDH1A1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684724-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-08-04 | — | — | US | claimed |
| EP-0462531-B1 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995029923-A1 | PROCESS FOR THE PREPARATION OF MONO- AND BIS(PHOSPHOCHOLINE) DERIVATIVES WHICH HAVE ANTIFUNGAL ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1995-11-09 | — | — | WO | disclosed |
| US-4332816-A | PHYTOPATHOGENS | CIBA-GEIGY CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |