Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.41 |
| ▸ | NMT2 | O60551 | 4/20 | 0.39 |
| ▸ | NMT1 | P30419 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174188 | 0.83 | TBXAS1 (0.52) | TBXAS1CYP19A1QPCTGAACYP2B6 | |
| SCHEMBL8164980 | 0.80 | CYP2B6 (0.46) | TBXAS1CYP19A1CYP2B6FDPS | |
| Hydrochloric Acid SCHEMBL10845833 | 0.78 | CYP2B6 (0.44) | TBXAS1CYP19A1QPCTCYP2B6FDPS | |
| SCHEMBL10844142 | 0.75 | CYP2B6 (0.49) | TBXAS1CYP19A1QPCTGAACYP2B6 | |
| SCHEMBL9253280 | 0.75 | TBXAS1 (0.71) | TBXAS1CYP19A1 | |
| SCHEMBL78110 | 0.75 | — | — | |
| Alcohol SCHEMBL28263377 | 0.74 | TBXAS1 (0.59) | TBXAS1CYP19A1QPCT | |
| Hydrochloric Acid SCHEMBL4781930 | 0.73 | TBXAS1 (0.68) | TBXAS1CYP19A1 | |
| Water SCHEMBL2854772 | 0.73 | TBXAS1 (0.68) | TBXAS1CYP19A1 | |
| Iodide SCHEMBL29834228 | 0.73 | TBXAS1 (0.68) | TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339702-A1 | 5-AMIDE SUBSTITUTED DIARYLAMINES AS MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2001068619-A1 | 5-AMIDE SUBSTITUTED DIARYLAMINES AS MEX INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-09-20 | — | — | WO | disclosed |