Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242854 | 0.88 | ITGA4 (0.52) | TSHRALDH1A1LMNACNR2MAPK1 | |
| SCHEMBL7216901 | 0.88 | NPC1 (0.43) | TSHRALDH1A1LMNACNR2TP53 | |
| SCHEMBL7217135 | 0.86 | ITGA4 (0.46) | TSHRALDH1A1LMNACNR2TP53 | |
| SCHEMBL7217612 | 0.86 | CYSLTR2 (0.42) | TSHRALDH1A1LMNACNR2NPC1 | |
| SCHEMBL6935238 | 0.85 | TSHR (0.47) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL6239930 | 0.85 | TSHR (0.47) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL7224601 | 0.85 | TSHR (0.47) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL6238689 | 0.84 | PDCD1 (0.44) | TSHRALDH1A1MAPK1POLBITGA4 | |
| SCHEMBL7217238 | 0.81 | TLR2 (0.43) | TSHRALDH1A1LMNACNR2NPC1 | |
| SCHEMBL7217619 | 0.81 | NOD1 (0.43) | TSHRALDH1A1LMNACNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552061-B1 | For therapy and prophylaxis of inflammatory skin injuries or diseases | AJINOMOTO CO., INC. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0955046-A2 | Amino acid derivatives and anti-inflammatory agents | Ajinomoto Co., Inc. (JP) | 1999-11-10 | — | — | EP | disclosed |