Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.62 |
| ▸ | ITGAV | P06756 | 20/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974536 | 1.00 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL7217620 | 0.93 | ITGB3 (0.66) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211544 | 0.92 | ITGB3 (0.64) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211458 | 0.87 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217773 | 0.87 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL7211471 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7212708 | 0.85 | ITGB3 (0.58) | ITGB3ITGAVITGA2B | |
| SCHEMBL7217507 | 0.84 | ITGB3 (0.87) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7974527 | 0.84 | ITGB3 (0.87) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217736 | 0.84 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620820-B2 | Imidazole dione or one, thione derivatives as antitumor and antiinflammatory agents, also treats cardiovascular disease, nephropathies and retinopathies | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-09-16 | — | — | US | disclosed |