Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.87 |
| ▸ | ITGAV | P06756 | 20/20 | 0.87 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.62 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217507 | 1.00 | ITGB3 (0.87) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217600 | 0.93 | ITGB3 (0.93) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211537 | 0.92 | ITGB3 (0.91) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211444 | 0.87 | ITGB3 (0.87) | ITGB3ITGAVITGA2B | |
| SCHEMBL7211462 | 0.86 | ITGB3 (0.82) | ITGB3ITGAVITGA2B | |
| SCHEMBL7212703 | 0.85 | ITGB3 (0.83) | ITGB3ITGAVITGA2B | |
| SCHEMBL7217525 | 0.84 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7974536 | 0.84 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217730 | 0.84 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL7211652 | 0.82 | ITGB3 (0.77) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218415-B1 | THERAPY OF BONE REABSORPTION BY OSTEOCLASTS, TUMOR GROWTH AND TUMOR METASTASIS, INFLAMMATION, CARDIOVASCULAR DISEASE, NEPHROPATHIES AND RETINOPATHIES | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-04-17 | — | — | US | disclosed |