Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223995 | 0.89 | SMN1; SMN2 (0.46) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL5941054 | 0.85 | NLRP3 (0.56) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL30502814 | 0.85 | NLRP3 (0.56) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL7225279 | 0.84 | SMN1; SMN2 (0.48) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL7225491 | 0.84 | SCN3A (0.46) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL7224255 | 0.82 | SCN3A (0.49) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL7223216 | 0.81 | NLRP3 (0.42) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL10348347 | 0.81 | PARP1 (0.49) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL7219434 | 0.81 | NLRP3 (0.49) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL7219478 | 0.81 | SMN1; SMN2 (0.46) | MEN1KMT2ACYP1A2CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |