Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217431 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7217581 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1LMNAEGFR | |
| SCHEMBL7224806 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2MAPTALDH1A1LMNAEGFR | |
| SCHEMBL7219630 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL7224215 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7223596 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTALDH1A1LMNAEGFR | |
| SCHEMBL7223947 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1LMNAEGFR | |
| SCHEMBL7223759 | 0.71 | ALDH1A1 (0.49) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7224466 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7225429 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |